Sertaconazole Nitrate Shows Fungicidal and Fungistatic Activities against Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum, Causative Agents of Tinea Pedis

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Sertaconazole nitrate shows fungicidal and fungistatic activities against Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum, causative agents of tinea pedis.

The fungistatic and fungicidal activities of sertaconazole against dermatophytes were evaluated by testing 150 clinical isolates of causative agents of tinea pedis, Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum. The overall geometric means for fungistatic and fungicidal activities of sertaconazole against these isolates were 0.26 and 2.26 μg/ml, respectively, al...

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since most of the studies on chemical compounds of dermatophytes have shown the existence of a relationship between their pathogenisity and proteolytec enzymes. activities of 19 different enzymes in viable mycelia and cytoplasmic extracts of t.rubrum (cetr), t.mentagrophytes (cetm) and t.verrucosum (cetv) were investigated by the api-zym system. the results showed that viable mycelia of t.rubrm...

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Degradation of Ethanol by Two Species of Dermatophytes: Trichophyton mentagrophytes and Epidermophyton floccosum

Ethanol is an important industrial product. It can be degraded by microorganisms to use as sole source of carbon. Trichophyton mentagrophytes and Epidermophyton floccosum are most known species of dermatophytes. Their ability to degrade ethanol was detected. Low concentrations of ethanol enhanced two tested species of dermatophytes to grow on culture medium faster in absence of carbon source. A...

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Antifungal activities of clove essential oil and its volatile vapour against dermatophytic fungi including Candida albicans, Epidermophyton floccosum. Microsporum audouinii, Trichophyton mentagrophytes, and Trichophyton rubrum were investigated. Both clove essential oil and its volatile vapour strongly inhibit spore germination and mycelial growth of the dermatophytic fungi tested. The volatile...

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 2011

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.00219-11